Jo Martin, 56, who plays Max McGerry in Holby City, revealed the sad news of her grand-nephew’s death at 21 on Instagram.
Taking to her page on Sunday, Jo shared the heartbreaking news of how her grand-nephew passed away on Christmas Day.
Sharing a snap of her grand-nephew, Jo penned a touching caption.
In the caption, the actress penned: “My beautiful Grand Nephew.
“He left us on Christmas morning 2025.
“RIP Isaiah.”
Jo concluded: “Truly heartbreaking only 21. Cancer is a bitch.”
In another post she said how she wished they could “bring him back” and explained how her family was “heartbroken”.
Fans and friends flocked to the comments section to sent messages of condolence to Jo and her family.
One person wrote: “I am so sorry. My heart goes out to you and your family.”
A second penned: “Please accept my deepest sympathies and condolences.
“Sending love and comfort to you and your family.
“May his soul rebirth in paradise.”
A third added: “I’m so so sorry Jo! Sending you and your family all my love!”
While a fourth said: “My love. I’m so sorry. What a heartbreaking loss for you and your family. Sending love.”
And a fifth penned: “This is a tragedy Jo. I’m so so sorry for your whole family. Prayers for his safe passage.”
On television, Jo is known for her several roles in various series and shows.
She is known for her work on the BBC series The Crouches as Natalie Crouch.
Jo is also known for starring in Back to Life as Janice, and Doctor Who as the Fugitive Doctor.
Jo has also worked on Dreaming Whilst Black playing Grace and The Marlow Murder Club playing Suzy Harris.